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Phase I/II Trial of Bevacizumab and Radiotherapy for Locally Advanced Inoperable Colorectal Cancer: Vasculature-Independent Radiosensitizing Effect of Bevacizumab
Clinical Cancer Research, 11/06/09
Koukourakis MI et al. – The combination of radiotherapy with bevacizumab is feasible and results in a high rate of durable complete responses in patients with LA/I–CRC. Radiosensitization may occur through a direct effect on tumor cells followed by a wide scale suppression of transcription factors and genes involved in DNA repair and proliferation.
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Today in Colorectal Cancer/Polyps...keeping you current
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A blood-based biomarker panel for stratifying current risk for colorectal cancer
International Journal of Cancer, 11/24/09
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells
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The importance of -460 C/T and +405 G/C single nucleotide polymorphisms to the function of vascular endothelial growth factor A in colorectal cancer
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Today in Pharmacology/Therapy...keeping you current
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Nuclear IRS-1 predicts tamoxifen response in patients with early breast cancer
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Successful treatment of autoimmune and lymphoproliferative complications of patients with intrinsic B-cell immunodeficiencies with Rituximab
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