Oncology Medical News about tumour permeability

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Increase in tumour permeability following TGF-beta type I receptor-inhibitor treatment observed by dynamic contrast-enhanced MRI
British Journal of Cancer, 11/06/09

Minowa T et al. – These findings suggest that DCE–MRI and, in particular, Ktrans and vp quantitation, provide important additional information about tumour vasculature by A–83–01 treatment.

Exclusive Author Commentary
Y Maitani, 11/07/09

Ktrans and vp showed a moderate negative correlation to apparent diffusion coefficient, suggesting that these parameters may be providing similar information. Since apparent diffusion coefficient is acquired in clinic widely to detect and diagnose a tumor, it could apply conveniently to examine the permeability of tumor in patients.

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The expression of p53, bcl-2, bax, fas and fasL in the primary tumour and lymph node metastases of breast cancer
Acta Oncologica, 11/02/09 Relevance Score: 48%

Primary postoperative chemotherapy without radiotherapy for treatment of brain tumours other than ependymoma in children under 3 years: Results of the first UKCCSG/SIOP CNS 9204 trial
European Journal of Cancer, 10/13/09 Relevance Score: 46%

Priming of immune responses against transporter associated with antigen processing (TAP)-deficient tumours: tumour direct priming
Immunology, 10/12/09 Relevance Score: 46%

Cutaneous metastasis from gastric glomus tumour
Clinical and Experimental Dermatology, 10/05/09 Relevance Score: 46%

Juxtarenal/pararenal Wilms’ tumour in a six-year-old Malay girl
Singapore Medical Journal, 10/05/09 Relevance Score: 46%