Oncology Medical News about claudin-1 expression

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HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability
Oncogene, 11/05/09

Krishnan M et al. – The authors report a novel post–transcriptional regulation of claudin–1 expression in colon cancer cells and further show a functional correlation between claudin–1 expression and TSA–mediated regulation of invasion. As HDAC inhibitors are considered to be promising anticancer drugs, these new findings will have implications in both laboratory and clinical settings.

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Changes in cell characteristics due to retinoic acid; specifically, a decrease in the expression of claudin-1 and increase in claudin-4 within tight junctions in stratified oral keratinocytes
Journal of Periodontal Research, 10/08/09 Relevance Score: 66%

Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization
Journal of Virology, 11/19/09 Relevance Score: 65%

Expression analysis of Notch-related molecules in peripheral blood T helper cells of patients with rheumatoid arthritis
Scandinavian Journal of Rheumatology, 10/01/09 Relevance Score: 48%

GPR30 and estrogen receptor expression: New insights into hormone dependence of inflammatory breast cancer
Breast Cancer Research and Treatment, 11/16/09 Relevance Score: 47%

Correlation of GREB1 mRNA with protein expression in breast cancer: validation of a novel GREB1 monoclonal antibody
Breast Cancer Research and Treatment, 11/04/09 Relevance Score: 47%