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Focal amplification and oncogene dependency of GAB2 in breast cancer
Oncogene, 11/05/09
Bocanegra M et al. – The studies implicate focal amplification of GAB2 in breast carcinogenesis, and underscore an oncogenic role of scaffolding adapter proteins, and a potential new point of therapeutic intervention.
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
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Today in Breast...keeping you current
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c-Jun activation is required for 4-hydroxytamoxifen-induced cell death in breast cancer cells
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