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See Latest ArticlesA common gain of function of p53 cancer mutants in inducing genetic instability
Oncogene, 11/05/09
Liu DP et al. – Considering the critical roles of ATM in maintaining genetic stability and therapeutic responses to many cancer treatments, the identification of this common gain of function of p53 cancer mutants will have important implication on the drug resistance of a significant portion of human cancers that express either the contact or structural p53 cancer mutants.
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