Oncology Medical News about luminal apoptosis

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1. Report Shows Shift in Starting Salaries for Physicians

2. Recommendations on the use of 18F-FDG PET in oncology

3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials

4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ

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BAG-1 overexpression attenuates luminal apoptosis in MCF-10A mammary epithelial cells through enhanced RAF-1 activation
Oncogene, 11/05/09

Anderson LR et al. – Reversal of the BAG–1–associated survival phenotype by the mitogen–activated kinase/ERK kinase inhibitor, U0126, implicates the RAF–1–extracellular signal–regulated kinase signaling pathway as a major mediator of BAG–1's effects in this model. As BAG–1 expression is often elevated in preinvasive breast cancers, these findings support a possible role for BAG–1 as an early contributor to the malignant process in the breast.

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Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition
Proceedings of the National Academy of Sciences of the United States of America, 11/18/09 Relevance Score: 45%

Lymphocyte apoptosis after major abdominal surgery is not influenced by anesthetic technique: a comparative study of general anesthesia versus combined general and epidural analgesia
Journal of Clinical Anesthesia, 10/19/09 Relevance Score: 44%

Berberine Induced Apoptosis via Promoting the Expression of Caspase-8, -9 and -3, Apoptosis-inducing Factor and Endonuclease G in SCC-4 Human Tongue Squamous Carcinoma Cancer Cells
Anticancer Research, 11/11/09 Relevance Score: 43%

Retinal Ganglion Cell Death Postponed: Giving Apoptosis a Break
Ophthalmic Research, 10/20/09 Relevance Score: 43%

Baculovirus DNA Replication-Specific Expression Factors Trigger Apoptosis and Shutoff of Host Protein Synthesis during Infection
Journal of Virology, 10/13/09 Relevance Score: 43%