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Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines
Molecular Carcinogenesis, 11/05/09
Beierle EA et al. – The results of the current study suggest that both FAK and Src play a role in protecting neuroblastoma cells from apoptosis, and that dual inhibition of these kinases may be important when designing therapeutic interventions for this tumor.
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Today in Basic Science/Genetics...keeping you current
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Identification of novel ER-alpha target genes in breast cancer cells: Gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17beta-estradiol and tamoxifen
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