Oncology Medical News about oligoastrocytoma

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Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination
Journal of Neuro-Oncology, 11/04/09

Passarin MG et al. – Leptomeningeal dissemination of low–grade gliomas is an uncommon event. This report describes a 43–year old male who presented with dizziness, gait ataxia, and diplopia. A nonenhancing lesion in the right cerebellar peduncle was identified, subtotally resected, and diagnosed as a grade II astrocytoma. Complete remission was achieved after 12 months of treatment and the patient is still free from the disease after a follow–up of 24 months. The authors suggest that this combination may be a valuable treatment option.

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NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
Journal of Clinical Oncology, 11/12/09 Relevance Score: 77%