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Prognostically significant cytotoxic T cell clones are stimulated after thalidomide therapy in patients with multiple myeloma
Leukemia and Lymphoma, 11/06/09
Brown RD et al. – Thalidomide did not appear to modulate Treg numbers. Expanded T cell clones are prognostically significant and have an impact on progression after thalidomide therapy in a proportion of patients.
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Today in Basic Science/Genetics...keeping you current
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A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk
Breast Cancer Research and Treatment, 11/24/09
Five common single nucleotide polymorphisms in the PALB2 gene and susceptibility to breast cancer in eastern Chinese population
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Association of rare MSH6 variants with familial breast cancer
Breast Cancer Research and Treatment, 11/24/09
Today in Myeloproliferative Dz...keeping you current
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Polycythemia vera erythroid precursors exhibit increased proliferation and apoptosis resistance associated with abnormal RAS and PI3K pathway activation
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Unrelated stem cell transplantation after reduced intensity conditioning for patients with multiple myeloma relapsing after autologous transplantation
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