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Herrington CS et al. – This paper exemplifies how the hypothesis–driven study of a rare syndrome can be highly effective at answering specific questions about disease processes. It is of note that recent evidence from the same group provides convincing evidence that the distal Fallopian tube may, in fact, be the commonest site of origin for high–grade pelvic serous carcinomas, most of which may originate at this site rather than from the ovary.

Today in Basic Science/Genetics...keeping you current

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British Journal of Haematology, 11/20/09

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Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis
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Today in Carcinogenesis...keeping you current

APC promoter hypermethylation is an early event in endometrial tumorigenesis
Cancer Science, 11/16/09

Biological role of NHERF1 protein expression in breast cancer
Histopathology, 11/12/09

Down-Regulation of FXYD3 Expression in Human Lung Cancers. Its Mechanism and Potential Role in Carcinogenesis
American Journal of Pathology, 11/09/09

Today in Gynecologic Oncology...keeping you current

Elevated expression of p53 gain-of-function mutation R175H in endometrial cancer cells can increase the invasive phenotypes by activation of the EGFR/PI3K/AKT pathway
Molecular Cancer, 11/20/09

Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors
Journal of Cancer Research & Clinical Oncology, 11/20/09

Macrophage migration inhibitory factor expression in cervical cancer
Journal of Cancer Research & Clinical Oncology, 11/20/09


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