Oncology Medical News about malignant glioma

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MK886-induced apoptosis depends on the 5-LO expression level in human malignant glioma cells
Journal of Neuro-Oncology, 11/04/09

Lim JY et al. – There is a link between the 5–LO expression status and the extent of MK886–inhibited cell proliferation and apoptosis. 5–LO is a possible target for treating patients with gliomas, and 5–LO inhibition might be potent therapy for patients with 5–LO–expressing malignant gliomas.

Methyl-L-11C-Methionine PET as a Diagnostic Marker for Malignant Progression in Patients with Glioma
The Journal of Nuclear Medicine, 11/18/09 Relevance Score: 67%

A Phase II Study of Cisplatin and Temozolomide in Heavily Pre-treated Patients with Temozolomide-refractory High-grade Malignant Glioma
Anticancer Research, 11/13/09 Relevance Score: 67%

Fibulin-3 Is Uniquely Upregulated in Malignant Gliomas and Promotes Tumor Cell Motility and Invasion
Molecular Cancer Research, 11/06/09 Relevance Score: 67%

Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma
Neuro-Oncology, 10/06/09 Relevance Score: 67%

Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab
Neuro-Oncology, 10/06/09 Relevance Score: 67%