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Management of major bleedings during anticoagulant treatment with the oral direct thrombin inhibitor ximelagatran or warfarin
Blood Coagulation & Fibrinolysis, 11/03/09
Fernlof G et al. – The case descriptions did not reveal any apparent differences in the course of events between groups. The authors found no indications that the lack of an antidote posed a clinical problem in patients treated with ximelagatran as compared with warfarin. The relatively short half–life of melagatran, the active metabolite of ximelagatran, may have contributed to these results.
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