Oncology Medical News about Thyroid Cancer

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Recommendations on the use of 18F-FDG PET in oncology

3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials

4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

The BRAFV600E Oncogene Induces Transforming Growth Factor beta Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer
Cancer Research, 11/02/09

Riesco–Eizaguirre G et al. – TGFbeta is overexpressed in the invasive front, whereas NIS is preferentially expressed in the central regions of the tumors, suggesting that this negative correlation between TGFbeta and NIS occurs locally inside the tumor. The study describes a novel mechanism of NIS repression in thyroid cancer and provides evidence that TGFbeta may play a key role in promoting radioiodide resistance and tumor invasion during PTC progression.

<< Previous
A Role for BRCA1 in Uterine Leiomyosarcoma

Next >>
Deletion of PTEN Promotes Tumorigenic Signaling, Resistance to...