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Your Article Summary

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Dai Y et al. – These data indicate that when MPS–1 is overexpressed, it has an extraribosomal function as a strong inhibitor of HNSCC tumor cell growth, which may be exerted by reduced paxillin gene expression.


Exclusive Author Commentary
Brendan C. Stack, 11/05/09

This article represents a first for consideration of the use of ribosomal proteins as a possible therapy for head and neck cancer. Ribosomal proteins are integral actors in cancer molecular biology. This class of peptides may offer new therapeutic options for many types of malignacies.

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