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See Latest ArticlesDo male lymphoma survivors have impaired sexual function?
Journal of Clinical Oncology, 10/29/09
Kiserud CE et al. – Sexual function in male lymphoma survivors was examined and compared with that of age-matched controls in this study. Lymphoma survivors had significantly poorer sexual function than normative controls. It is unclear whether the abnormal hormone levels directly cause the reduced sexual function within the lymphoma group or if a mediating factor is involved, such as aging, emotional distress, or perceived health status.
Methods- Cross-sectional study
- Serum gonadal hormone levels (testosterone, sex hormone–binding globulin, luteinizing hormone [LH], and follicle-stimulating hormone) and responses to questionnaires assessing sexual function (Brief Sexual Function Inventory [BSFI]), socioeconomic factors, quality of life, emotional distress, and fatigue included
- Lymphoma group included 246 men 50 years old at diagnosis diagnosed from 1980 to 2002
- For each lymphoma survivor, 2 age-matched controls were drawn from normative sample with BSFI scores
- Lymphoma survivors had mean age at survey of 47.4 years, mean duration of follow-up 14.8 years, and 79% lived in committed relationships
- All BSFI domain scores decreased significantly with age
- Lymphoma survivors having low testosterone and/or elevated LH had lower BSFI scores than survivors with normal gonadal hormones
- Multivariate analyses showed increasing age, more emotional distress, poor physical health, and low testosterone and/or elevated LH significantly associated with reduced sexual function within lymphoma group
- Lymphoma survivors had significantly lower BSFI domain scores than did controls on erection, ejaculation, and sexual satisfaction
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