Oncology Medical News about xenobiotic receptor

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Steroid and xenobiotic receptor in human esophageal squamous cell carcinoma: A potent prognostic factor
Cancer Science, 11/02/09

Takeyama D et al. – Results of quantitative RT–PCR study demonstrated that SXR mRNA expression was detected in three of five cases, and was marked higher in the cancerous tissue than non–neoplastic tissue of these patients. This is the first study to demonstrate the status of SXR in human ESCC and the results suggest that SXR is a potent favorable prognostic factor of human ESCC.

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Xenobiotic-Sensing Nuclear Receptors CAR and PXR as Drug Targets in Cholestatic Liver Disease
Current Drug Targets, 11/03/09 Relevance Score: 66%

Evolution, body composition, insulin receptor competition, and insulin resistance
Preventive Medicine, 11/02/09 Relevance Score: 47%

Targeting the NMDA Receptor Subunit NR2B for the Treatment of Neuropathic Pain
Neurotherapeutics, 10/05/09 Relevance Score: 47%

Cardiovascular disease-related genes and regulation by diet
Current Atherosclerosis Reports, 11/17/09 Relevance Score: 46%

The prognostic significance of single hormone receptor positive metastatic breast cancer: An analysis of three randomised phase III trials of aromatase inhibitors
The Breast, 10/21/09 Relevance Score: 46%