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T-box-expressed-in-T-cells (T-bet) expression by the tumor cells of hairy cell leukemia correlates with interferon-gamma production
Leukemia and Lymphoma, 10/30/09
Johrens K et al. – Based on the recent findings that a non–neoplastic B–cell subset, the monocytoid B–cells, are T–bet positive and produce IFN–gamma, the authors propose that monocytoid and hairy B–cells have a similar function and that the T–bet–IFN–gamma axis is involved in the pathogenesis of HCL.
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Today in Basic Science/Genetics...keeping you current
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Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia
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Today in Leukemia/Lymphoma...keeping you current
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Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia
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