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p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy
Leukemia and Lymphoma, 10/30/09
Schlette EJ et al. – Patients with p53–IHC(+) CLL were less likely to achieve complete remission, but patients who did achieve complete remission showed a durable response. In this patient cohort, p53–IHC is an important determinant of complete remission and overall survival, but not remission duration, in patients with CLL receiving FCR.
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