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See Latest ArticlesThe impact of carcinoembryonic antigen flare in patients with advanced colorectal cancer receiving first-line chemotherapy
Annals of Oncology, 11/03/09
Strimpakos AS et al. – Compared with patients with rising CEA, flare was an independent favourable predictive and prognostic factor for tumour response and survival.
Methods- Patients with histologically proven advanced colorectal cancer undergoing first-line chemotherapy with three or more serial CEA measurements (one at baseline and two or more during treatment) included
- Grouped according to CEA kinetic as flare (F), decreasing CEA, normal baseline CEA, stable CEA and increasing CEA (I)
- From January 2000 to February 2008, 837 patients screened
- 670 patients eligible
- CEA flare occurred in 78 (11.6%) patients
- On multivariate analysis, compared with patients with increasing CEA, patients with CEA flare had significantly better ORR , PFS and OS
Today in Colorectal Cancer/Polyps...keeping you current
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A randomized trial on folic acid supplementation and risk of recurrent colorectal adenoma
American Journal of Clinical Nutrition, 10/29/09
Localized resection for colon cancer
Surgical Oncology, 11/04/09
Extended lymphadenectomy versus conventional surgery for rectal cancer: a meta-analysis : The Lancet Oncology
The Lancet Oncology - Online First, 10/23/09
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