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See Latest ArticlesAssessment of breast cancer opportunistic screening by clinical-pathological indicators: A population-based study
British Journal of Cancer, 10/30/09
Bordoni A et al. – Some clinical–pathological features of breast cancers, such as the incidence of ductal cancer in situ (DCIS) and the diameter of invasive tumours, are sensitive indicators of early detection. An opportunistic screening strategy can lead to an improvement of prognostic features at diagnosis, but these features are still less favourable than those achieved by organised screening programmes.
Methods- Cases of DCIS or invasive breast cancer diagnosed in 1996–2007 identified
- Time trends of age-adjusted incidence and mortality, as well as main clinical–pathological features, such as tumour diameter, AJCC stage and histological grade, analysed
- Total of 3047 incident cases of female breast cancer identified
- Proportion of DCIS with respect to invasive cases increased from 5.8% in period 1996–2001 to 6.4% in period 2002–2007
- Median tumour size of invasive cancers decreased from 20 mm in 1996–2001 to 18 mm in 2002–2007
- Increase in well/moderately differentiated invasive tumours, from 67% in period 1996–2001 to 73% in 2002–2007 , was detected and resulted in Annual Percentage Change of incidence of 2.8 (95% confidence interval: 1.3; 4.3)
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