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Quantitative decision-making in preimplantation genetic (aneuploidy) screening (PGS)
Journal of Assisted Reproduction and Genetics, 10/26/09
Summers MC et al. – The authors set out the statistical framework to determine the limits of PGS when a specific number of day 3 preimplantation embryos are available for biopsy. In general, PGS cannot be recommended a priori for a specific clinical situation due to the statistical uncertainties associated with the different hidden variable quantitative parameters considered important to the clinical outcome
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