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See Latest ArticlesLimitations of the ristocetin cofactor assay in measurement of von Willebrand factor function
Journal of Thrombosis and Haemostasis, 10/28/09
Flood VH et al. – The decreased VWF:RCo seen with the P1467S sequence variation likely represents an artifact as a result of the use of ristocetin to measure VWF activity. The normal VWF function in other assays correlates with the lack of hemorrhagic symptoms, and suggests the need for more physiologically relevant assays of VWF function.
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