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Evaluation of anti-activated protein C antibody development in patients with severe sepsis from four clinical studies with drotrecogin alfa (activated)
Journal of Thrombosis and Haemostasis, 10/27/09
Yan SB et al. – The proportion of patients with anti–APC antibodies was low and was similar between DAA–treated and placebo–treated patients. No relationship between anti–APC antibody development and adverse reactions was observed. There was no evidence that the anti–APC antibodies detected represented a specific immune response to DAA therapy.
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Today in Coagulation/Bleeding Dz...keeping you current
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