Oncology Medical News about Pituitary Adenomas

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Signalling Pathway Alterations in Pituitary Adenomas: Involvement of Gsalpha, cAMP and Mitogen-Activated Protein Kinases
Journal of Neuroendocrinology, 11/03/09

Pertuit M et al. – In the light of results obtained on human somatotroph adenoma cells in primary culture and on models of murine somatotroph cell lines, the authors postulate a crucial role for ERK1/2 in GH–secreting adenomas downstream of cAMP pathway alterations that might impact the tumoural phenotype.

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