Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
Top Ten Searches
brca1 prostate-specific antigen sclc fobt egd bmi dysplasia hematologic ovarian hccYour Article Summary
See Latest ArticlesMeta- and Pooled Analyses of the Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Colorectal Cancer: A HuGE-GSEC Review
American Journal of Epidemiology, 10/22/09
Taioli E et al. – The MTHFR 677TT polymorphism seems to be associated with a reduced risk of CRC, but this may not hold true for all populations.
Methods- The authors performed both a meta–analysis (29 studies; 11,936 cases, 18,714 controls) and a pooled analysis (14 studies; 5,068 cases, 7,876 controls) of the C677T MTHFR polymorphism and CRC, with stratification by racial/ethnic population and behavioral risk factors.
- There were few studies on different racial/ethnic populations.
- The overall meta–analysis odds ratio for CRC for persons with the TT genotype was 0.83.
- An inverse association was observed in whites and Asians but not in Latinos or blacks.
- Similar results were observed for Asians, Latinos, and blacks in the pooled analysis.
- Similar results were observed for Asians, Latinos, and blacks in the pooled analysis.
Related Articles
Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: The FOCUS Trial
Journal of Clinical Oncology, 10/30/09
Relevance Score: 78%
P73 expression and its clinical significance in colorectal cancer
Colorectal Disease, 10/19/09
Relevance Score: 68%
Surgical management of colorectal liver metastases
Community Oncology, 10/09/09
Relevance Score: 68%
The effect of aspirin in the recurrence of colorectal adenomas: a meta-analysis of randomized controlled trials
Colorectal Disease, 10/15/09
Relevance Score: 67%
Aspirin as Colorectal Cancer Adjuvant Therapy
Gastroenterology, 10/05/09
Relevance Score: 67%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Gene-expression-based analysis of local and metastatic neuroblastoma variants reveals a set of genes associated with tumor progression in neuroblastoma patients
International Journal of Cancer, 12/15/09
BEX2 regulates mitochondrial apoptosis and G1 cell cycle in breast cancer
International Journal of Cancer, 12/15/09
Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells
International Journal of Cancer, 12/15/09
Today in Colorectal Cancer/Polyps...keeping you current
Receive free subspecialty "5-minute updates" via email
Role of Notch signaling in colorectal cancer
Carcinogenesis, 12/15/09
Physical activity and male colorectal cancer survival
Archives of Internal Medicine, 12/15/09
Long-term outcomes after hepatic resection for colorectal metastases in young patients
Cancer, 12/15/09
Sponsor
Article Search
Sponsor
Sponsor