Oncology Medical News about Cytokeratin 8 ectoplasmic domain

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Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness
Molecular Cancer, 10/28/09

Obermajer N et al. – These novel findings suggest a model in which CK8, together with uPA, plasminogen and fibronectin, constitutes a signaling platform capable of modulating cell adhesion/growth–dependent signal transduction in breast tumor cells. Anti–CK MAb, which competes for the binding site for uPA, could be used as an agent to reduce the invasive potential of breast tumor cells.

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Nursing Students Response to Tobacco Cessation Curricula in Minnesota Baccalaureate Nursing Programs
Journal of Nursing Education, 10/19/09 Relevance Score: 64%

Long-Term Follow-up of Adolescent Idiopathic Scoliosis Patients Who Had Harrington Instrumentation and Fusion to the Lower Lumbar Vertebrae: Is Low Back Pain a Problem?
Spine, 11/13/09 Relevance Score: 62%

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The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1 alpha in human rheumatoid arthritis fibroblast-like synoviocyte
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The Crystal Structure of PF-8, the DNA Polymerase Accessory Subunit from Kaposi's Sarcoma-Associated Herpesvirus
Journal of Virology, 11/13/09 Relevance Score: 45%