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Identification of molecular targets associated with transformed diffuse large B cell lymphoma using highly purified tumor cells
American Journal of Hematology, 10/27/09

Andreasson U et al. – The authors demonstrate that by purifying tumor cells through cell sorting, thereby reducing the heterogeneity due to infiltrating cells, it was possible to identify distinct differences between tumor entities rather than variations due to cellular composition. Galectin–3 and NEK2 both identified a subgroup of DLBCL–tr, and the function of these protein markers also suggests a biological role in the transformation process.

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