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Long-term and recent recreational physical activity and survival after breast cancer: The California Teachers Study
Cancer Epidemiology, Biomarkers & Prevention, 10/26/09
West-Wright CN et al. – Consistent long-term participation in physical activity before breast cancer diagnosis may lower risk of breast cancer death, providing further justification for public health strategies to increase physical activity throughout the lifespan.
Methods- California Teachers Study cohort members provided information in 1995-1996 on long-term (high school through age 54 years) and recent (past 3 years) participation in moderate and strenuous recreational physical activities
- 3,539 women diagnosed with invasive breast cancer after cohort entry and through December 31, 2004 followed through December 31, 2005
- Moderate and strenuous physical activities combined into low (≤ 0.50 h/wk/y of any activity), intermediate (0.51-3.0 h/wk/y of moderate or strenuous activity but no activity > 3.0 h/wk/y), or high activity (> 3.0 h/wk/y of either activity type)
- Multivariable relative risks (RR) and 95% confidence intervals (95% CI) for mortality estimated using Cox proportional hazards methods, adjusting for race/ethnicity, estrogen receptor status, disease stage, and baseline information on comorbidities, BMI, and caloric intake
- 460 women died, 221 from breast cancer
- Women with high or intermediate levels of long-term physical activity had lower risk of breast cancer death than women with low activity levels
- Associations consistent across estrogen receptor status and disease stage, but confined to overweight women
- Deaths due to causes other than breast cancer related only to recent activity
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