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See Latest ArticlesGenetic Variants of Methyl Metabolizing Enzymes and Epigenetic Regulators: Associations with Promoter CpG Island Hypermethylation in Colorectal Cancer
Cancer Epidemiology, Biomarkers & Prevention, 10/27/09
de Vogel S et al. – MTHFR, MTR, DNMT3b, and EHMT2 polymorphisms are associated with colorectal cancer, and rare variants of MTR and MTRR may reduce promoter hypermethylation. The incomplete overlap between CIMP, MLH1 hypermethylation, and microsatellite instability indicates that these related "methylation phenotypes" may not be similar and should be investigated separately.
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Today in Basic Science/Genetics...keeping you current
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Expression of p16 in benign and malignant cystic squamous lesions of the neck
Human Pathology, 12/19/09
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Today in Colorectal Cancer/Polyps...keeping you current
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Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression
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