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Dendritic Cell Transfected with Secondary Lymphoid-Tissue Chemokine and/or Interleukin-2 Gene-Enhanced Cytotoxicity of T-Lymphocyte in Human Bladder Tumor Cell S In Vitro
Cancer Investigation, 10/26/09
Li Y–G et al. – SLC and IL–2 were produced by autocrine in DCs transfected with SLC and IL–2 genes. DC/SLC–IL–2 can promote DC proliferation, while TC–DC/SLC–IL–2 and TC–DC/SLC could strongly enhance significant cytotoxicity against bladder cancer cell that was induced by the coculture of DCs (transfected with SLC and IL–2) and TC.
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