Oncology Medical News about Iron Chelation Therapies

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A New Era in Iron Chelation Therapy: The Design of Optimal, Individually Adjusted Iron Chelation Therapies for the Complete Removal of Iron Overload in Thalassemia and other Chronically Transfused Patients
Hemoglobin, 10/23/09

Kontoghiorghes GJ – A major aspect of the improved therapies is the ability of L1 to mobilize and remove excess cardiac iron and reduce congestive cardiac failure, which is the main cause of death in thalassemia patients. Further, new developments include the use of alternating sequential chelation therapies and selected dose protocols with L1, DFO and deferasirox (DFRA) for overcoming toxicity and efficacy complications observed in some patients treated with monotherapies or combination therapies.

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Iron Chelation Therapy for Patients with Myelodysplastic Syndrome
Hemoglobin, 10/23/09 Relevance Score: 81%

Uses and Limitations of Serum Ferritin, Magnetic Resonance Imaging T2 and T2* in the Diagnosis of Iron Overload and in the Ferrikinetics of Normalization of the Iron Stores in Thalassemia Using the International Committee on Chelation Deferiprone/Deferoxamine Combination Protocol
Hemoglobin, 10/23/09 Relevance Score: 81%

Understanding Iron Overload:Screening, Monitoring, and Caring for Patients With Transfusion-Dependent Anemias
Clinical Journal of Oncology Nursing, 10/06/09 Relevance Score: 81%

Iron overload and toxicity: the hidden risk of multiple blood transfusions
Vox Sanguinis, 10/06/09 Relevance Score: 80%

Iron chelation therapy in the management of thalassemia: the Asian perspectives
International Journal of Hematology, 11/04/09 Relevance Score: 79%