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A Practical Chelation Protocol Based on Stratification of Thalassemic Patients by Serum Ferritin and Magnetic Resonance Imaging Cardiac T2*
Hemoglobin, 10/23/09
Ha S–Y et al. – The previous study showed that combined therapy with deferiprone (L1) and deferoxamine (DFO) was safe and efficacious in reducing iron overload in poorly–chelated thalassemia major patients for the short–term but the magnetic resonance imaging (MRI) T2* evaluation was not available at that time. All Group A patients continued with DFO treatment. In Group B, seven were on Regimen Ii, five on Regimen II and five on Regimen III. In Group C, five were on Regimen Ii, two on Regimen II and 26 on Regimen III. Significant improvement was noted only for Group C patients using Regimen III (combined therapy) in SF levels, cardiac T2* and liver T2* measurements.
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Update on the use of deferasirox in the management of iron overload
Therapeutics and Clinical Risk Management, 11/05/09
Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia
European Journal of Haematology, 11/04/09
Effect of Epoetin Alfa on Survival and Cancer Treatment-Related Anemia and Fatigue in Patients Receiving Radical Radiotherapy With Curative Intent for Head and Neck Cancer
Journal of Clinical Oncology, 11/09/09
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