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Sanoff HK et al. – The authors recommend vinflunine 300 mg/m^2 and pemetrexed 500 mg/m^2 in combination every 3 weeks for future study. At these doses, the combination of vinflunine and pemetrexed was tolerable in this heavily pretreated population. Hematologic toxicity, including febrile neutropenia, was prominent.



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