Oncology Medical News about Mycophenolate Mofetil

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An Age Dependent Pharmacokinetic Study of Intravenous and Oral Mycophenolate Mofetil in Combination with Tacrolimus for GVHD Prophylaxis in Pediatric Allogeneic Stem Cell Transplantation Recipients
Biology of Blood and Marrow Transplantation, 10/22/09

Bhatia M et al. – There was a significant increase in MPA exposure on Day +14 vs day +7 suggesting improved enterohepatic recirculation at day +14 post AlloSCT. Children less than 12 yrs of age appear to have a significantly different MPA PK profile compared to older children and adolescents and may require more frequent dosing.

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