Oncology Medical News about Mucositis

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Mucositis: The impact, biology and therapeutic opportunities of oral mucositis
Oral Oncology , 10/21/09

Sonis ST – While the FDA’s approval of palifermin in 2004 was limited to only a small percentage of the at–risk population, the fact that the first registered anti–OM agent derived its efficacy from its pleotropic activities was conceptually demonstrative of the therapeutic potential of drugs that selectively interfere with mucositis’ pathogenesis. A number of eclectic molecules, all designed to interfere with pathways that lead to injury are in pre–clinical and clinical development.

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Explorative study on the predictive value of systematic inflammatory and metabolic markers on weight loss in head and neck cancer patients undergoing radiotherapy
Supportive Care in Cancer, 10/20/09 Relevance Score: 82%

Effect of topical morphine (mouthwash) on oral pain due to chemotherapy- and/or radiotherapy-induced mucositis: a randomized double-blinded study
Journal of Palliative Medicine, 10/19/09 Relevance Score: 82%

Long-term outcome of mesna, ifosfamide, mitoxantrone, etoposide (MINE) regimen as a consolidation in patients with aggressive non-Hodgkin lymphoma responding to CHOP
Medical Oncology, 10/06/09 Relevance Score: 80%

Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial
The Lancet Oncology - Online First, 10/30/09 Relevance Score: 77%

Phase II study of docetaxel, cisplatin, and 5-FU induction chemotherapy followed by chemoradiotherapy in locoregionally advanced nasopharyngeal cancer
Cancer Chemotherapy and Pharmacology, 10/21/09 Relevance Score: 77%