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See Latest ArticlesThymosin beta4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma
Haematologica, 10/21/09
Caers J et al. – Thymosin beta 4 (Tbeta4) is a polypeptide involved in cellular proliferation, differentiation, and migration, overexpressed in several tumor–entities. In 209 MM–patients treated with high–dose therapy and autologous stem cell transplantation, expression of Tbeta4 below the median was associated with a significantly shorter event–free survival. In conclusion, the results indicate a possible tumor suppressive function of Tbeta4.
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
Oncogene, 11/25/09
A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy
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Embryoid body formation of human amniotic fluid stem cells depends on mTOR
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Today in Myeloproliferative Dz...keeping you current
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Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs
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International Prognostic Scoring System-independent cytogenetic risk categorization in primary myelofibrosis
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Polycythemia vera erythroid precursors exhibit increased proliferation and apoptosis resistance associated with abnormal RAS and PI3K pathway activation
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