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See Latest ArticlesErythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin
Haematologica, 10/21/09
Ashby DR et al. – Expression of hepcidin, the key hormone governing iron transport, is reduced by anemia, in a manner which appears dependent on increased bone marrow activity. The temporal associations between plasma hepcidin and other iron parameters were examined in healthy humans after erythropoietin administration and venesection. These human studies confirm the importance of a rapidly responsive marrow–hepcidin axis in regulating iron supply in vivo, and suggest that this axis is regulated by factors other than circulating iron, soluble transferrin receptor or growth differentiation factor–15.
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Today in Anemia/Polycythemia...keeping you current
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Unpredictability of iv Busulfan pharmacokinetics in children undergoing hematopoietic stem cell transplant for advanced beta thalassemia: Limited toxicity with a dose adjustment policy
Biology of Blood and Marrow Transplantation, 12/09/09
Molecular Analysis of gamma-Globin Promoters, HS-111 and 3'HS1, in beta-thalassemia Intermedia Patients Associated with High Levels of Hb F
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Molecular Characterization of a Novel 55.1 kb Ggamma(Agammadeltabeta)0-thalassemia Deletion in Two Canadian Families
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Today in Basic Science/Genetics...keeping you current
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Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Proceedings of the National Academy of Sciences of the United States of America, 12/09/09
A gene expression signature that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy
Breast Cancer Research and Treatment, 12/09/09
Expression of Hiwi in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
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