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RAS Mutations Affect Tumor Necrosis Factor–Induced Apoptosis in Colon Carcinoma Cells via ERK-Modulatory Negative and Positive Feedback Circuits Along with Non-ERK Pathway Effects
Cancer Research, 10/27/09
Kreeger PK et al. – The findings indicate that diverse RAS mutations yield differential cell behavioral responses to inflammatory cytokine exposure by means of differential effects on ERK activity via multiple feedback circuit mechanisms and differential effects on other key signaling pathways contextually modulating ERK–related dependence.
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Today in Basic Science/Genetics...keeping you current
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Activating Peroxisome Proliferator-Activated Receptor gamma Mutant Promotes Tumor Growth In vivo by Enhancing Angiogenesis
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Extracellular Signal–Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression
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Today in Colorectal Cancer/Polyps...keeping you current
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Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression
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Phase II Trial of Infusional Fluorouracil, Irinotecan, and Bevacizumab for Metastatic Colorectal Cancer: Efficacy and Circulating Angiogenic Biomarkers Associated With Therapeutic Resistance
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Sunlight, hormone replacement status and colorectal cancer risk in postmenopausal women
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