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Cost-effectiveness of CT and PET-CT for determining the need for adjuvant neck dissection in locally advanced head and neck cancer
Annals of Oncology, 10/20/09
Sher DJ et al. – Patients with node–positive head and neck squamous cell carcinomas (HNC) have a significant risk of residual disease (RD) in the neck after treatment, despite optimal chemoradiotherapy (CRT). Adjuvant neck dissection (ND) after CRT has been considered standard treatment, but its morbidity has led investigators to consider using post–CRT imaging to determine the need for surgery. Adjuvant ND reserved for patients with RD on PET–CT is the dominant and cost–effective strategy.
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