Oncology Medical News about graft-versus-host disease

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Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
Blood, 11/02/09

Jasperson LK et al. – Administration of an agonist to toll–like receptor (TLR)–7/8, a receptor expressed primarily on APCs, induced IDO and reduced injury in the colon, and ameliorated lethality. IDO upregulation may have therapeutic potential for preventing GVHD in the clinic.

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Immunomonitoring of graft-versus-host minor histocompatibility antigen correlates with graft-versus-host disease and absence of relapse after graft
Transfusion, 10/26/09 Relevance Score: 66%

Platelet gel for treatment of mucocutaneous lesions related to graft-versus-host disease after allogeneic hematopoietic stem cell transplant
Transfusion, 10/13/09 Relevance Score: 65%

Interleukin 17 Is Not Required for Autoimmune-Mediated Pathologic Damage during Chronic Graft-versus-Host Disease
Biology of Blood and Marrow Transplantation, 10/07/09 Relevance Score: 65%

Oral Chronic Graft-versus-Host Disease Scoring Using the NIH Consensus Criteria
Biology of Blood and Marrow Transplantation, 10/07/09 Relevance Score: 65%

Pre-Engraftment Syndrome after Double Unit Cord Blood Transplantation: A Distinct Syndrome not Associated with Acute Graft-Versus-Host Disease
Biology of Blood and Marrow Transplantation, 10/29/09 Relevance Score: 64%