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In utero exposure to therapeutic radiation for Hodgkin lymphoma
Canadian Family Physician, 10/14/09
Klieger–Grossmann C et al. – Congenital anomalies and growth impairment have been reported in infants and adolescents exposed in utero to radiation; however, most studies show that delayed growth and malformations occur following high doses of ionizing radiation, mostly greater than 50 cGy. Thus, radiotherapy should not be an absolute contraindication in pregnant patients diagnosed with cancer located remote from the pelvic area (eg, breast cancer, brain tumours, head and neck tumours, and supradiaphragmatic tumours). In such cases, the fetal radiation dose and the predictive effects should be estimated by qualified medical personnel (ie, a radiation physicist or radiation oncologist) and discussed with the woman (or the couple) on an individual basis to allow an optimally informed decision. Close prenatal follow–up of structural abnormalities, as well as of fetal growth and neurodevelopment, is indicated in these cases.
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Today in Leukemia/Lymphoma...keeping you current
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Final analysis of the UKLG LY02 trial comparing 6–8 cycles of CHOP with 3 cycles of CHOP followed by a BEAM autograft in patients <65 years with poor prognosis histologically aggressive NHL
British Journal of Haematology, 03/19/10
Review of phenotypic markers used in flow cytometric analysis of MGUS and MM, and applicability of flow cytometry in other plasma cell disorders
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High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy
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Today in Pharmacology/Therapy...keeping you current
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Phase II study of paclitaxel and vinorelbine (Pacl-Vin) in hormone-refractory metastatic prostate cancer: double tubulin targeting
Internal Medicine Journal, 03/19/10
Anticancer effects of CAMEL peptide
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High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy
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Today in Side Effects...keeping you current
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Practical considerations in the management of hand-foot skin reaction caused by multikinase inhibitors
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Esophageal Strictures During Treatment for Acute Lymphoblastic Leukemia
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Menopausal symptoms in women undergoing chemotherapy-induced and natural menopause: a prospective controlled study
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