Oncology Medical News about monoclonal gammopathies

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Risk of progression in smouldering myeloma and monoclonal gammopathies of unknown significance: comparative analysis of the evolution of monoclonal component and multiparameter flow cytometry of bone marrow plasma cells
British Journal of Haematology, 10/16/09

Perez–Persona E et al. – The present study explored the impact of two novel criteria; having >95% abnormal plasma cells by flow cytometry at diagnosis and the evolving subtype of the disease, as predictors of progression in 61 smouldering multiple myeloma (SMM) and 311 monoclonal gammopathy of unknown significance (MGUS) patients. Immunophenotyping discriminated the different risk of progression within the evolving and non–evolving subgroups of SMM and MGUS.

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Brain metastases admissions in Sweden between 1987 and 2006

Sporadic late onset nemaline myopathy responsive to IVIg and immunotherapy
Muscle & Nerve, 11/06/09 Relevance Score: 64%

Prognostic value of regulatory T cells, lymphoma-associated macrophages, and MUM-1 expression in follicular lymphoma treated before and after the introduction of monoclonal antibody therapy: A Southwest Oncology Group Study
Annals of Oncology, 11/09/09 Relevance Score: 43%

Pim-1 expression and monoclonal antibody targeting in human leukemia cell lines
Experimental Hematology, 10/22/09 Relevance Score: 42%

An IgA1-lambda-type monoclonal immunoglobulin deposition disease associated with membranous features in a patient with chronic hepatitis C viral infection and rectal cancer
Clinical and Experimental Nephrology, 10/05/09 Relevance Score: 42%

Sanofi-aventis and U.S. Biotechnology company Merrimack enter into an Exclusive Global Collaboration and Licensing Agreement for a monoclonal antibody in Oncology
Sanofi-aventis, 10/02/09 Relevance Score: 42%