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Extracorporeal membrane oxygenation as a rescue therapy for leukaemic children with pulmonary failure
British Journal of Haematology, 10/16/09
Meister B et al. – In patients with leukaemia, acute respiratory distress syndrome (ARDS) secondary to intensified chemotherapy–induced immunosuppression is a devastating disorder resulting in high morbidity and mortality. Compared to standard indications for extracorporeal membrane oxygenation (ECMO), cytopenia further increases the risks of infection and bleeding. ECMO is a supportive tool to reduce the incidence of early death, treatment–related mortality and, ultimately, to improve overall survival in childhood leukaemia.
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