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Monitoring of minimal residual disease in acute myeloid leukemia
Current Opinion in Oncology, 10/13/09
Buccisano F et al. – Studies of MRD should provide us the opportunity to generate comprehensive prognostic algorithms which take into account conventional parameters, such as cytogenetic and genetic profile, and those strictly inherent to the quality of response, such as determination of residual leukemia. This will greatly enhance development of personalized therapeutic approaches, avoiding the situation of under or over drug exposure.
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