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Evidence-based evaluation of the risks of malignancy predicted by thyroid fine-needle aspiration biopsies
Diagnostic Cytopathology, 10/14/09
Marchevsky AM et al. – A National Cancer Institute (NCI) "Thyroid Fine–Needle Aspiration (FNA) State of the Science Conference" recently proposed standardized nomenclature and "risks of malignancies" associated with various diagnostic categories. The authors evaluated the evidence levels of the data used by NCI to predict malignancy risks and whether those estimates had clinical validity in the patient population. Relative risk and 95% CI calculations suggested that the NCI classification could be simplified into three categories: "benign", "FLUS + neoplasm", and "suspicious + malignant".
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