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Underweight and breast cancer recurrence and death: A report from the Korean breast cancer society
Journal of Clinical Oncology, 10/08/09

Moon HG et al. – Our study suggests that underweight should be considered to be a high risk factor for death and recurrence after breast cancer surgery, especially in Asian breast cancer patients.

• Investigated this issue using a large nationwide database of 24,698 Korean breast cancer patients
• Association between body weight status and breast cancer recurrence further explored using a single-institution database containing information on 4,345 patients

• Results from nationwide database showed significantly lower OS and breast cancer-specific survival (BCSS) in underweight patients compared with survival in patients of normal weight
• Adjusted for known prognostic factors such as age, tumor size, lymph node metastasis, hormone receptor status, histologic grade, and lymphovascular invasion
• Not observed in obese patients
• In analysis of recurrence data from single institution, underweight women had significantly higher risk of both distant metastasis and local recurrence of breast cancer

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