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Phase I Study of Ipilimumab, an Anti–CTLA-4 Monoclonal Antibody, in Patients with Relapsed and Refractory B-Cell Non–Hodgkin Lymphoma
Clinical Cancer Research, 10/12/09
Ansell SM et al. – Blockade of CTLA–4 signaling with the use of ipilimumab is well tolerated at the doses used and has antitumor activity in patients with B–cell lymphoma. Further evaluation of ipilimumab alone or in combination with other agents in B–cell lymphoma patients is therefore warranted.
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