Oncology Medical News about HGF/Met signalling

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HGF/Met signalling promotes PGE2 biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells
Carcinogenesis, 10/08/09

Moore AE et al. – The data reveal a critical role for HGF/Met signalling in promoting PGE2 biogenesis in colorectal cancer cells. Targeting the crosstalk between these two important pathways may be useful for therapeutic treatment of colorectal cancer.

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Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting
BMC Cancer, 11/02/09 Relevance Score: 45%

Characterisation of the activated liver progenitor cell niche, potential involvement of Wnt and Notch signalling
Gut, 11/09/09 Relevance Score: 43%

Expression of NF-kappaB and IkappaB proteins in skeletal muscle of gastric cancer patients
European Journal of Cancer, 10/29/09 Relevance Score: 42%

Genetic deficiencies of innate immune signalling in human infectious disease : The Lancet Infectious Diseases
The Lancet Infectious Diseases, 10/27/09 Relevance Score: 42%

Notch-1 signalling is activated in brain arteriovenous malformations in humans
Brain, 10/23/09 Relevance Score: 42%