Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
Top Ten Searches
brca1 prostate-specific antigen sclc fobt egd bmi dysplasia hematologic ovarian hccYour Article Summary
A novel functional variant (–842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity
Carcinogenesis, 10/08/09
Lu J et al. – The –842G allele had a higher activity than that driven by the –842C allele, suggesting that the –842C allele was associated with a reduced transcriptional activity, a finding consistent with a reduced risk observed in the case–control analysis. Large prospective studies of diverse ethnic groups and diverse cancer sites are warranted to validate the findings.
Related Articles
Promoter hypermethylation mediates downregulation of thiamine receptor slc19a3 in gastric cancer
Tumor Biology, 10/12/09
Relevance Score: 45%
Detection of MGMT Promoter Methylation in Normal Individuals Is Strongly Associated with the T Allele of the rs16906252 MGMT Promoter Single Nucleotide Polymorphism
Cancer Prevention Research, 10/08/09
Relevance Score: 45%
RANTES Promoter Genotype and Gastric Cancer Risk in a Japanese Population
Anticancer Research, 11/13/09
Relevance Score: 44%
APC promoter hypermethylation is an early event in endometrial tumorigenesis
Cancer Science, 11/16/09
Relevance Score: 43%
Novel Role of Pin1 Induction in Type II Collagen-Mediated Rheumatoid Arthritis
Journal of Immunology, 11/09/09
Relevance Score: 43%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Thrombopoietin in normal and neoplastic stem cell development
Best Practice & Research: Clinical Haematology , 12/07/09
Mechanisms of mutations in myeloproliferative neoplasms
Best Practice & Research: Clinical Haematology , 12/07/09
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma
International Journal of Cancer, 12/07/09
Today in Head and Neck...keeping you current
Receive free subspecialty "5-minute updates" via email
Radiation Treatment Interruptions Greater Than One Week and Low Hemoglobin Levels (12 g/dL) are Predictors of Local Regional Failure After Definitive Concurrent Chemotherapy and Intensity-Modulated Radiation Therapy for Squamous Cell Carcinoma of the Head and Neck
American Journal of Clinical Oncology, 12/07/09
Failure to Diagnose and Delayed Diagnosis of Cancer
The Journal of the American Dental Association , 12/07/09
Prospective study of daily low-dose nedaplatin and continuous 5-fluorouracil infusion combined with radiation for the treatment of esophageal squamous cell carcinoma
BMC Cancer, 12/04/09
Sponsor
Article Search
Sponsor
Sponsor


See Latest Articles


