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Oncogenic Ras, but not V600EB-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells
Carcinogenesis, 10/08/09
Calleros L et al. – The data demonstrate that low levels of cholesterol induce apoptosis in colorectal cancer cells without oncogenic Ras mutations. The results reveal a novel molecular characteristic of colon tumours containing Ras or B–RAF mutations and should help in defining new targets for cancer therapy.
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Today in Basic Science/Genetics...keeping you current
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Today in Colorectal Cancer/Polyps...keeping you current
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